From the category archives:

Cervical Cancer

For a comprehensive review of literature dispelling the myth that there is a big difference between high risk and low risk patients and screening for cervical cancer please read NUNS, VIRGINS, AND SPINSTERS’. RIGONI-STERN AND CERVICAL CANCER REVISITED, MALCOLM GRIFFITHS.

Put simply,  over a long period of time a concept often explained and often repeated, acquires an authoritative stature it may not deserve .  The concept’s very foundation may be faulty but the “test of time”  is no test  if, in all the retellings, the foundation is never reexamined.

In his article, Griffiths examines the much quoted proposition that low risk women do not require rigorous screening for cervical cancer.   Who is at lower risk than a nun?  It turns out this is a trick question because the risk of developing cervical cancer is about the same for a nun as an unmarried women and about half that of married women.

In the debate surrounding screening for cancer advocates of opposing positions tend to pick and believe evidence which agrres with therir respective positions.  This is a debate in which women cannot afford to be driven by bias.  They deserve the truth, their lives depend upon it.

For further information on cervical cancer and the importance of proper cancer screening see Meyersmedmal.com

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According to the American Cancer Society’s most recent estimate for 2009, 11,270 new cases of invasive cervical cancer will be diagnosed and 4,070 women will die from the disease.

Prior to 1955 cervical cancer was one of the most common causes of cancer death for American women. As a result of the development of the Pap smear screening test between 1955 and 1992, the cervical cancer death rate declined by 74%.

Since half of the cervical cancer cases arise in patients who have never had a Pap smear or whose last Pap smear preceded diagnosis of invasive cancer by more than five years, the problem is not that too many Pap smears are being done but that not enough Pap smears are being done.

Nevertheless, the guidelines for screening of Pap smears have resulted in fewer Pap smears being done. For a test that is misinterpreted when it shows abnormalities between 20 and 40% of the time, frequent repetition of the test is needed to assure one appropriate interpretation. Even when an appropriate interpretation of Pap smears is made and abnormalities are found which require treatment, the appropriate treatment is not given 10% of the time.

For a test associated with little cost, and which is essentially risk free, the pressure to limit the performance of even this test is clearly present.

Matthew Mintz, M.D. writes at KevinMD.com medical web blog on November 17, 2009, “Why Doctors are Doing So Many Unnecessary Pap Smears.” In his opinion piece, Dr. Mintz asserts that the Pap smear is a symbol of our healthcare system’s problems, yet the only evidence he quotes in support of this proposition is a study from the Annuals of Internal Medicine which demonstrates doctors are doing more frequent Pap smears on women than some guidelines recommend.

The fact that more Pap smears are being done does not mean that they are needless and they certainly are not harmful.

When even well-informed physicians can reach such wrong-headed conclusions it is not surprising that it is so difficult to fix the healthcare system.

Where is the alarm about the high rate at which Pap smears are wrongly interpreted as negative when in fact they show ominous changes?

Not all screening tests have been as successful as the Pap smear. The fact that we could have for example better screening tests for breast cancer than a mammogram does not negate the importance of women having an option to have a mammogram. We should be searching for better screening tests improving the performance of existing texts and not failing to screen with the tests available simply because the tests are imperfect.

With such controversy swirling about healthcare reform it is difficult to hear the truth in the midst of all the noise that is being made. Staying well informed and being skeptical is the safest approach to receiving appropriate medical care.

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Gardasil, a Good Idea?

by Jerry Meyers

Gardasil is a HPV vaccine produced by Merck.  HPV, Human Papilloma Virus, has clearly been demonstrated to increase the risk of a woman developing cervical cancer so it would seem to be a good idea to provide young woman, even as teenagers, with a vaccine that would guard against the virus and prevent the development [...]

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Patients Not Informed of Clinically Significant Outpatient Test Results

by Jerry Meyers

The Archives of Internal Medicine, June 22, 2009, published results of a retrospective medical record review involving nineteen community based and four academic medical center primary care practices.  The researchers were intent upon examining how frequently patients were not informed of clinically significant abnormal outpatient test results.  The researcher’s conclusion was that it is common [...]

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Study in rural India has positive implications for the value of HPV screening for cervical cancer in the USA.

by Jerry Meyers

The April 2, 2009 Issue of the New England Journal of Medicine includes a report of a study recently concluded concerning the value of HPV screening for cervical cancer in rural India.
HPV stands for Human Papilloma Virus. The current standard of practice in the United States requires that all women be tested for the presence [...]

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Women Beware – Your rights to proper and regular screening for cervical cancer by pap smears and other means is being attacked.

by Jerry Meyers

In a recent publication of a British Medical Journal (October 13, 2008), the findings of a joint European study are reported. The purpose of the study was to establish whether frequent HPV and Pap smears are really necessary. On the basis of their study they concluded that screening at six-year intervals would be safe and [...]

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